Preparation method for optimizing pummelo peel tire formula granules based on response surface method

The invention discloses a preparation method for optimizing pummelo peel embryo formula granules based on a response surface method.The preparation method comprises the steps that the mass ratio of an excipient to freeze-dried powder, the ethanol concentration and the ethanol dosage serve as investigation factors, total evaluation serves as an evaluation index, and factor level experiment design is conducted according to the Box-behnken design response surface method; and carrying out secondary multiple regression fitting analysis on the data by applying Design-Expert software, and optimizing to obtain the preparation process of the exocarpium citri grandis embryo formula granules. The preparation method for optimizing the pummelo peel embryo formula granules by combining a single factor test with a response surface method is adopted, the effective component content and the effective component transfer rate of the pummelo peel embryo formula granules prepared by the method are high, the consistency of the eff