Proteolytic enzyme mixtures for treatment of psoriasis

The present invention provides a method of treating a skin manifestation of psoriasis, the method comprising topically applying a pharmaceutical composition to an affected skin region of a subject, thereby treating a skin manifestation of psoriasis, the pharmaceutical composition comprises a partially purified proteolytic enzyme mixture obtained from crude bromelain and a pharmaceutically acceptable carrier. 本发明提供了治疗银屑病的皮肤表现的方法，该方法包括向受试者的受影响的皮肤区域局部应用药物组合物，从而治疗银屑病的皮肤表现，所述药物组合物包含从粗制菠萝蛋白酶获得的部分纯化的蛋白水解酶混合物和药学上可接受的载体。