IgA nephropathy model based on tear as well as establishment method and application of IgA nephropathy model

IgA nephropathy model based on tear as well as establishment method and application of IgA nephropathy model

The invention relates to a tear-based IgA nephropathy model as well as an establishment method and application thereof. A tear-based IgA nephropathy model establishment method is characterized by comprising the following steps: (1) selecting an IgA nephropathy patient and a healthy control group, co...

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Hauptverfasser: CHEN CHEN, TAN JIQIANG
Format: Patent
Sprache:chi ; eng
Schlagworte:
CALCULATING
COMPUTER SYSTEMS BASED ON SPECIFIC COMPUTATIONAL MODELS
COMPUTING
COUNTING
ELECTRIC DIGITAL DATA PROCESSING
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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creator CHEN CHEN
TAN JIQIANG
description The invention relates to a tear-based IgA nephropathy model as well as an establishment method and application thereof. A tear-based IgA nephropathy model establishment method is characterized by comprising the following steps: (1) selecting an IgA nephropathy patient and a healthy control group, collecting tear samples, and storing the tear samples at-80 DEG C; (2) data collection: taking out a tear sample during an experiment, unfreezing the tear sample at normal temperature, and recording a tear Raman spectrum by using a confocal Raman spectrometer; (3) data preprocessing: after a fluorescence background is deducted from the tear Raman spectrum, normalization processing is carried out; and (4) establishing a classification model by adopting the preprocessed data, namely the IgA nephropathy model. According to the tear-based IgA nephropathy model as well as the establishment method and the application thereof, the Raman spectrum is combined with the deep learning method, so that the tear-based IgA nephropat
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A tear-based IgA nephropathy model establishment method is characterized by comprising the following steps: (1) selecting an IgA nephropathy patient and a healthy control group, collecting tear samples, and storing the tear samples at-80 DEG C; (2) data collection: taking out a tear sample during an experiment, unfreezing the tear sample at normal temperature, and recording a tear Raman spectrum by using a confocal Raman spectrometer; (3) data preprocessing: after a fluorescence background is deducted from the tear Raman spectrum, normalization processing is carried out; and (4) establishing a classification model by adopting the preprocessed data, namely the IgA nephropathy model. 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subjects CALCULATING
COMPUTER SYSTEMS BASED ON SPECIFIC COMPUTATIONAL MODELS
COMPUTING
COUNTING
ELECTRIC DIGITAL DATA PROCESSING
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title IgA nephropathy model based on tear as well as establishment method and application of IgA nephropathy model
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