IgA nephropathy model based on tear as well as establishment method and application of IgA nephropathy model

The invention relates to a tear-based IgA nephropathy model as well as an establishment method and application thereof. A tear-based IgA nephropathy model establishment method is characterized by comprising the following steps: (1) selecting an IgA nephropathy patient and a healthy control group, collecting tear samples, and storing the tear samples at-80 DEG C; (2) data collection: taking out a tear sample during an experiment, unfreezing the tear sample at normal temperature, and recording a tear Raman spectrum by using a confocal Raman spectrometer; (3) data preprocessing: after a fluorescence background is deducted from the tear Raman spectrum, normalization processing is carried out; and (4) establishing a classification model by adopting the preprocessed data, namely the IgA nephropathy model. According to the tear-based IgA nephropathy model as well as the establishment method and the application thereof, the Raman spectrum is combined with the deep learning method, so that the tear-based IgA nephropat