Visual intelligent induction controlled-release antibacterial coating as well as preparation method and application thereof

The invention belongs to the technical field of medical materials, and particularly relates to a visual intelligent induction controlled-release antibacterial coating as well as a preparation method and application thereof. The visual intelligent induction controlled-release antibacterial coating disclosed by the invention is prepared from oxidized carboxymethyl cellulose, hydrogel prepared from chitosan, polypeptide FK13-a1, an antibiotic meropenem and a pH indicator. The amino acid sequence of the polypeptide FK13-a1 provided by the invention is as shown in SEQ ID NO. 1. The controlled-release antibacterial coating provided by the invention has relatively remarkable antibacterial activity. Moreover, a visual monitoring system is established, a basis is provided for early diagnosis of bacterial infection, unnecessary invasive detection of a patient is reduced, intelligent controlled release of the coating is achieved, response drug release can be made according to the bacterial infection condition, an antiba