Acetylcysteine oral preparation and preparation method thereof

The invention provides an acetylcysteine oral preparation and a preparation method thereof. The preparation comprises 25% (w/w) of acetylcysteine, 0.5-1.5% (w/w) of povidone k30, 35-45% (w/w) of a diluent, 3-10% (w/w) of a disintegrating agent, 10-15% (w/w) of a filler, 8-13% (w/w) of sodium bicarbonate, 0.5-1.5% (w/w) of a flow aid, 2-4% (w/w) of a flavoring agent and 0.5-1.5% (w/w) of a lubricant, and the sum of the mass percentages of the components is 1. The acetylcysteine tablet is prepared by adopting acetylcysteine for pre-coating, then mixing with other auxiliary materials and directly tabletting powder, the auxiliary materials are reasonable in type selection and scientific in proportion, the finished product is good in quality stability and rapid in disintegration, the preparation process is simple, the operation is convenient, and the acetylcysteine tablet is suitable for industrial large-scale production. 本发明提供一种乙酰半胱氨酸口服制剂及其制备方法，该制剂组方包括乙酰半胱氨酸25％(w/w)、聚维酮k300.5-1.5％(w/w)、稀释剂35-45％(w/w)、崩解剂3-10％(w/w