Immunomodulators

Immunomodulators

The present disclosure provides novel macrocyclic peptides that inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for ameliorating various diseases, including cancer and infectious diseases. 本公开文本提供了新型大环肽，其抑制PD-1/PD-L1和PD-L1/CD80蛋白/蛋白相互作用，因此可用于改善各种疾病，包括癌症和感染性疾病。...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ZHANG YUNHUI, QIAO, JENNIFER, X, ALLEN MARTIN PATRICK, POSS, MATTHEW, A
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present disclosure provides novel macrocyclic peptides that inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for ameliorating various diseases, including cancer and infectious diseases. 本公开文本提供了新型大环肽，其抑制PD-1/PD-L1和PD-L1/CD80蛋白/蛋白相互作用，因此可用于改善各种疾病，包括癌症和感染性疾病。