Application of molecular marker related to occurrence of teenager glaucoma and detection kit thereof

The invention provides a molecular marker related to occurrence of teenager type glaucoma. The molecular marker comprises the following genes: CRYBB3, FOXC1, GJA1, ADAMTS17, FBN1, AGBL1, FOXC2, LTBP2, MYOC, BCOR, PITX2, CPAMD8, JAG1, BMP4, TEK and CYP1B1. The invention further provides application o...

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Bibliographische Detailangaben
Hauptverfasser:	CHEN YUHONG, SHI WEIJIE, ZHANG YOUJIA, CHEN WENYE, CHEN CHENGWEN, XU QINGDAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides a molecular marker related to occurrence of teenager type glaucoma. The molecular marker comprises the following genes: CRYBB3, FOXC1, GJA1, ADAMTS17, FBN1, AGBL1, FOXC2, LTBP2, MYOC, BCOR, PITX2, CPAMD8, JAG1, BMP4, TEK and CYP1B1. The invention further provides application of the molecular marker in preparation of products for screening or auxiliary diagnosis of teenager glaucoma. The invention also provides a screening or auxiliary diagnosis kit for teenager glaucoma. The molecular marker is used for screening or auxiliary diagnosis of teenager type glaucoma and is high in sensitivity and specificity, the kit prepared from the molecular marker can reduce the cost of single detection and screening, meanwhile, the detection rate of teenager type glaucoma is remarkably increased, and the accuracy, sensitivity, specificity and stability of the kit are higher. 本发明提供了一种与青少年型青光眼发生相关的分子标记物，包括以下基因：CRYBB3、FOXC1、GJA1、ADAMTS17、FBN1、AGBL1、FOXC2、LTBP2、MYOC、BCOR、PITX2、CPAMD8、JAG1、BMP4、TEK和CYP1B1。本发