Micron biological material with bone-like structure as well as preparation method and application of micron biological material

The invention relates to the technical field of biomedical materials, in particular to a micron biological material with a bone-like structure as well as a preparation method and application of the micron biological material. The preparation method comprises the steps that mesenchymal stem cells are...

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Bibliographische Detailangaben
Hauptverfasser:	LIU YAN, GUO HOUZUO, LI ZIXIN, CUI SHENGJIE, FU YU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to the technical field of biomedical materials, in particular to a micron biological material with a bone-like structure as well as a preparation method and application of the micron biological material. The preparation method comprises the steps that mesenchymal stem cells are subjected to mineralization culture, an improved mineralization culture medium is used in the culture process, the improved mineralization culture medium comprises vancomycin, and the concentration of the vancomycin is 0.1-1.0 mM. The research finds that the vancomycin is added in the process of preparing the micron biological material based on the mesenchymal stem cells, so that the differentiation of the mesenchymal stem cells in the self-assembly process can be effectively promoted, and the micron biological material with a bone-like structure, which is higher in development degree and more complete in collagenous fiber structure, is formed. The micron biological material prepared by the preparation method prov