Medicinal preparation and application thereof

The invention relates to the technical field of medicines, and discloses a medicinal preparation and application thereof. The pharmaceutical preparation comprises the following components: pregnenolone 16 alpha-nitrile and pharmaceutically acceptable auxiliary materials or carriers. The invention provides a novel application of a medicinal preparation. The medicinal preparation comprises pregnenolone 16 alpha-nitrile. The inventor finds that the medicinal preparation can be used for preparing medicines for improving peritoneal structure damage and hypofunction caused by long-term peritoneal dialysis; the compound can be used for preparing drugs for improving peritoneal ultrafiltration function decline and glucose transport function decline caused by long-term peritoneal dialysis. The compound can be used for preparing drugs for reducing mesothelial mesenchymal transition of peritoneal mesothelial cells caused by long-term peritoneal dialysis. The compound can be used for preparing medicines for improving peri