Yttrium [90Y] microsphere as well as preparation method and application thereof

The invention relates to the technical field of radiopharmaceutical preparations, in particular to yttrium [90Y] microspheres and a preparation method and application thereof.The yttrium [90Y] microspheres comprise polystyrolsulfon acid type resin microspheres and yttrium-90 adsorbed in the polystyrolsulfon acid type resin microspheres, when the polystyrolsulfon acid type resin microspheres are adopted for adsorbing the yttrium-90, the adsorption strength is obviously improved, and the adsorption efficiency is improved. The safety in the preparation and use processes is obviously improved, and the killing effect on tumor cells is better. 本发明涉及放射性药物制剂技术领域，具体涉及一种钇[90Y]微球及其制备方法和用途，包括聚苯乙烯磺酸型树脂微球和吸附在所述聚苯乙烯磺酸型树脂微球内的钇-90，采用聚苯乙烯磺酸型树脂微球吸附钇-90具有明显提高的吸附强度，制备以及使用过程中的安全性均明显提高，且对肿瘤细胞的杀伤效果较好。