Hollow sponge bone needle as well as preparation method and application thereof

The invention discloses a hollow sponge bone needle as well as a preparation method and application thereof, and particularly discloses a preparation method of a hollow sponge bone needle taking a bee sponge bone needle and the like as basic raw materials and characterization data processed by the preparation method. According to the preparation method, an alkaline solution prepared from sodium hydroxide is used as a treating agent, and the sponge spicule is soaked and vibrated, so that the purpose that the alkaline solution reacts with silicon substances contained in the spicule is achieved, and a hollow channel is formed in the spicule. Furthermore, the efficiency of transdermal delivery of drugs is improved, the utilization rate of the drugs is improved, and more efficient, stable and safe transdermal absorption of a series of biomacromolecules such as active ingredients of drugs and cosmetics is greatly promoted. 本发明公开了中空海绵骨针及其制备方法和应用，具体公开了一种以蜂海绵骨针等为基础原料的中空海绵骨针制备方法，及其在制备方法处理后的表征数据。该制备方法以氢氧化钠配置的碱性溶液作为处理剂，将