Self-foaming expansion composite bone cement with high drug release property and preparation method of self-foaming expansion composite bone cement
The invention discloses self-foaming expansion composite bone cement with high drug release property and a preparation method thereof, and belongs to the technical field of biomedical material preparation methods. The self-foaming expansion composite bone cement with high drug release property is pr...
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| creator | WU ZIXIANG HE WEILIANG ZHANG BO YANG XUANZHE TAN QUANCHANG HU XIAOFAN HUANG JINFENG |
| description | The invention discloses self-foaming expansion composite bone cement with high drug release property and a preparation method thereof, and belongs to the technical field of biomedical material preparation methods. The self-foaming expansion composite bone cement with high drug release property is prepared from a solid-phase component and a liquid-phase component, the ratio of the solid phase component to the liquid phase component is 1g: (0.36-0.44) ml; the solid phase component is prepared from the following components in percentage by mass: 60%-72.7% of polymethyl methacrylate, 4%-12% of citric acid, 4%-12% of sodium bicarbonate, 11%-13% of zirconium dioxide, 0.5%-0.7% of benzoyl peroxide, 0.9%-1% of gentamicin sulfate and the balance of vancomycin; and the liquid phase component is a mixed solution of methyl methacrylate and N, N-dimethyl p-toluidine in a mass ratio of (97.5-98.5): (1.5-2.5). The self-foaming expansion composite bone cement prepared by the invention has good mechanical properties and extre |
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| subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL |
| title | Self-foaming expansion composite bone cement with high drug release property and preparation method of self-foaming expansion composite bone cement |
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