Markers for early detection of colonic cell proliferative disorders

The systems, media, compositions, methods, and kits disclosed herein relate to a panel of protein biomarkers for the early detection of colonic cell proliferative disorders, including colorectal cancer. The presence and levels of proteins in biological samples for the protein groups described herein can be used for classifier generation and as inputs in machine learning models that can be used to classify subjects in a population to detect colonic cell proliferative disorders. 本文公开的系统、介质、组合物、方法和试剂盒涉及用于包括结直肠癌在内的结肠细胞增殖性病症的早期检测的蛋白质生物标志物小组。用于本文所描述的蛋白质小组的生物样品中蛋白质的存在和水平可以用于分类器生成，并且用作可用于对群体中的对象进行分类以检测结肠细胞增殖性病症的机器学习模型中的输入。