POLYPEPTIDE PROCESSING AND ANALYSIS METHOD

Provided herein are methods for analyzing polypeptides and polypeptide complexes. The methods of the present disclosure can be used to identify protein subunits present in polypeptides, polypeptide complexes, or aggregates. These methods may also be used to quantify subunits (e.g., the number of rep...

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Bibliographische Detailangaben
Hauptverfasser: SWAMINATHAN JAGANNATH, BALDO ANDREW M, MARCOTTE EDWARD, ANSLYN ERIC
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided herein are methods for analyzing polypeptides and polypeptide complexes. The methods of the present disclosure can be used to identify protein subunits present in polypeptides, polypeptide complexes, or aggregates. These methods may also be used to quantify subunits (e.g., the number of repeat units, protein monomers, repeat domains) in polypeptides, polypeptide complexes or aggregates. 本文提供了用于分析多肽和多肽复合物的方法。本公开内容的方法可以用于鉴定在多肽、多肽复合物或聚集体中存在的蛋白质亚基。这些方法还可以用于定量在多肽、多肽复合物或聚集体中的亚基(例如重复单元、蛋白单体、重复结构域的数目)。