Application of benzamide derivative in pharmaceutical preparation for preventing and treating inflammatory injury

The invention relates to application of a benzamide derivative in a pharmaceutical preparation for preventing and treating inflammatory injury, and the applicant finds that the benzamide derivative can be used as a pharmaceutical preparation for preventing and/or treating cell inflammatory injury ca...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ZHANG SHUYU, YU DAOJIANG, GENG FENGHAO, LI XIAOQIAN
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to application of a benzamide derivative in a pharmaceutical preparation for preventing and treating inflammatory injury, and the applicant finds that the benzamide derivative can be used as a pharmaceutical preparation for preventing and/or treating cell inflammatory injury caused by factors such as radiation or microbial infection. The compound is proved to have the effects of inhibiting pyroptosis of cells, promoting healing of mouse radiation composite wounds and relieving inflammatory response of tissues induced by new coronal pseudoviruses. 本申请涉及苯甲酰胺衍生物在防治炎性损伤药物制剂中的用途,申请人发现苯甲酰胺衍生物能作为预防和/或治疗由辐射或微生物感染等因素所致细胞炎性损伤的药物制剂,在其中一些实施例中,证明了其具有抑制细胞焦亡、促进小鼠放射复合伤愈合和减轻新冠假病毒诱导组织炎症反应的作用。