Capsule type inhalation powder inhalation and preparation method thereof

The invention belongs to the technical field of biological medicines, and relates to a medicinal preparation, in particular to a capsule type inhalation powder inhalation and a preparation method thereof. The active ingredient of the capsule type inhalation dry powder inhalation is glycopyrronium bromide, the content of glycopyrronium bromide in each capsule is not higher than 20.0 micrograms based on glycopyrronium bromide, and the FPF in aerodynamic characteristics is 50.0-75.0%. According to the capsule type inhalation powder inhalation provided by the invention, the medication safety can be remarkably improved on the premise of ensuring the drug effect. 本发明属于生物医药技术领域，涉及药物制剂，具体涉及一种胶囊型吸入粉雾剂及其制备方法。胶囊型吸入粉雾剂的活性成分为格隆溴铵，格隆溴铵以格隆铵计在每粒胶囊中的含量不高于20.0μg，空气动力学特征中的FPF为50.0～75.0％。本发明提供的胶囊型吸入粉雾剂能够在保证药效的前提下，显著提升用药安全性。