High-throughput detection method for fat-soluble synthetic dye in food

The invention provides a high-throughput detection method for fat-soluble synthetic dyes in food, which comprises the following steps: 1) extracting and centrifuging a sample to obtain a sample extracting solution, diluting the sample extracting solution, and performing dispersive solid-phase extraction and purification to obtain a sample test solution; and 2) determining by adopting an ultra-high performance liquid chromatography quadrupole static electron orbit ion trap mass spectrometry sample test solution, establishing a correction curve by using a matrix standard solution, and quantifying by using an external standard method. The invention establishes a method for screening and quantitatively detecting 104 fat-soluble synthetic dyes in food, a sample is extracted, diluted and purified, a Fullms-ddMS2 mode of ultra-high performance liquid chromatography-high resolution mass spectrometry is used for determination, and the content of the 104 fat-soluble synthetic dyes in the food is determined through firs