Application of hydroxysafflor yellow A in treatment of platelet-related diseases

The invention relates to application of hydroxysafflor yellow A in treatment of platelet-related diseases, in particular to application of hydroxysafflor yellow A in preparation of a composition, and the composition is used for preventing and/or treating the platelet-related diseases. The invention...

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Hauptverfasser: YAO WENDONG, FAN QIAOMEI, JIANG JIALI, XIE XIANZE, WENG YAYUN, HUANG WEI, SHI ZHENG, ZHANG SHUO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to application of hydroxysafflor yellow A in treatment of platelet-related diseases, in particular to application of hydroxysafflor yellow A in preparation of a composition, and the composition is used for preventing and/or treating the platelet-related diseases. The invention finds that the hydroxysafflor yellow A can reduce the quantity of platelets, reduce the ratio of large platelets and inhibit the agglutination and aggregation of the platelets, and is used for preventing and treating diseases related to increase of the quantity of the platelets, such as thrombocytosis, diseases related to increase of the ratio of the large platelets and diseases related to platelet activation; therefore, diseases related to platelets are prevented and treated. 本发明涉及羟基红花黄色素A在治疗与血小板相关的疾病中的用途,具体地,本发明提供一种羟基红花黄色素A的用途,用于制备组合物,所述的组合物用于预防和/或治疗与血小板相关的疾病。本发明发现羟基红花黄色素A能够降低血小板的数量和降低大血小板比率,以及抑制血小板的凝集和聚集,用于预防和治疗与血小板数量升高相关的疾病如血小板增多症、与大血小板比率升高相关的疾病和血小板活化相关的疾病,从而预防和治疗与血小板相关的疾病。