Pyrrolopyrimidine or pyrrolopyridine derivative and medical application thereof
The invention relates to a pyrrolopyrimidine or pyrrolopyridine derivative and a medical application thereof. Specifically, the compound has a structure as shown in a formula I, has a good inhibition effect on focal adhesion kinase (FAK), inhibits related signal channels of the FAK, can be used for...
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| Format: | Patent |
| Sprache: | chi ; eng |
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| Zusammenfassung: | The invention relates to a pyrrolopyrimidine or pyrrolopyridine derivative and a medical application thereof. Specifically, the compound has a structure as shown in a formula I, has a good inhibition effect on focal adhesion kinase (FAK), inhibits related signal channels of the FAK, can be used for treating or preventing related diseases such as cancers, pulmonary arterial hypertension and pathological angiogenesis, and especially can be used for treating diseases caused by excessive or abnormal cell proliferation. , for example, tumors or cancers. # imgabs0 #
一种吡咯并嘧啶类或吡咯并吡啶类衍生物及其医药用途。具体地，所述化合物具有式Ⅰ所示结构，其对黏着斑激酶(FAK)具有较好的抑制作用，同时抑制其相关信号通路，可制备用于治疗或预防癌症、肺动脉高压、病理性血管生成等相关疾病，尤其可用于治疗由过度或异常细胞增殖引起的疾病，如肿瘤或癌症的药物。#imgabs0# |
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