Application of anti-MATR3 autoantibody reagent in preparation of product for detecting nervous system autoimmune diseases and kit

The invention discloses application of an anti-MATR3 autoantibody reagent in preparation of a product for detecting nervous system autoimmune diseases and a kit, and belongs to the technical field of biological medicines. Experiments prove that MATR3 can be used as one of recognition antigens of an...

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Hauptverfasser: LIU RUIMAN, SUN MINMIN, CHAI SHANSHAN, WANG YU, LIU KEXIN, XI QIAN, REN NI, LIU HUI, LI KE, HAO WENBIN, ZHANG ZHEWEI, YANG ZI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of an anti-MATR3 autoantibody reagent in preparation of a product for detecting nervous system autoimmune diseases and a kit, and belongs to the technical field of biological medicines. Experiments prove that MATR3 can be used as one of recognition antigens of an autoantibody related to the central nervous system autoimmune disease for the first time, especially MS related diseases, and an anti-MATR3 autoantibody reagent can achieve auxiliary diagnosis of the central nervous system autoimmune disease. 本发明公开了抗MATR3自身抗体的试剂在制备检测神经系统自身免疫疾病的产品中的应用及试剂盒,属于生物医药技术领域。本发明首次通过实验证实MATR3可作为中枢神经系统自身免疫疾病相关自身抗体的识别抗原之一,尤其是MS相关疾病,抗MATR3自身抗体的试剂能够实现中枢神经系统自身免疫疾病的辅助诊断。