Bovine nodular skin disease virus strain, inactivated vaccine prepared from bovine nodular skin disease virus strain and preparation method of vaccine

The invention provides a bovine nodular skin disease virus strain, an inactivated vaccine prepared from the bovine nodular skin disease virus strain and a preparation method of the vaccine, and belongs to the technical field of veterinary biological products. The bovine nodular skin disease virus strain LSDV/CH/JY/2021 provided by the invention is strong in virulence, good in immunogenicity, high in homology with existing strains at home and abroad, and suitable for producing broad-spectrum inactivated vaccines. The LSDV inactivated vaccine provided by the invention has high safety and strong immune efficacy, is suitable for industrial large-scale production, and is beneficial to prevention and control of bovine nodular skin diseases. 本发明提供一种牛结节性皮肤病病毒毒株、由该毒株制备的灭活疫苗和疫苗的制备方法，属于兽用生物制品技术领域。本发明提供的牛结节性皮肤病病毒毒株LSDV/CH/JY/2021的毒力强，免疫原性好，且与国内外现有毒株的同源性高，适合用于生产广谱性灭活疫苗。本发明提供的LSDV灭活疫苗安全性高、免疫效力强，且适于工业化大规模生产，有利于预防和控制牛结节性皮肤病。