Novel polycyclic indole derivative and preparation method thereof

The invention relates to the technical field of chemical synthesis, in particular to a novel polycyclic indole derivative and a preparation method thereof. The polycyclic indole derivative has a polycyclic structure formed by sharing indole nitrogen atoms and C7-site carbon atoms, and the general fo...

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Hauptverfasser: XU GEYING, GONG CHENG, CHANG HENG, WANG LIANG, MEI YINA, GONG SILIN, LIU CAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of chemical synthesis, in particular to a novel polycyclic indole derivative and a preparation method thereof. The polycyclic indole derivative has a polycyclic structure formed by sharing indole nitrogen atoms and C7-site carbon atoms, and the general formula of the chemical structure of the polycyclic indole derivative is as shown in the formula 1: # imgabs0 #, in the formula 1, a substituent group R1 comprises at least one of hydrogen, alkyl, alkoxy, alkoxycarbonyl, cyano, nitro and halogen; the substituent R2 comprises at least one of phenyl, second substituted phenyl, alkyl, aryl substituted alkyl and naphthalene ring; through a substitution reaction and a cyclization reaction based on the compound I, C7 site substitution of the compound I can be efficiently utilized to form a polycyclic indole derivative with a new structure, so that a synthesis path of a new indole derivative can be explored; the method is of great significance to rapid construction of indol