Preparation method and application of boron affinity surface imprinting adsorbent based on attapulgite

The invention belongs to the field of functional material preparation, and discloses a preparation method of a nystatin adsorbent based on attapulgite. The preparation method comprises the following specific preparation steps: (1) pretreating attapulgite; (2) coating the surface of the pretreated at...

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Hauptverfasser: YAN XINGCHEN, LI HENGYU, PAN JIANMING, ZHANG HENG, ZHANG QIUXIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the field of functional material preparation, and discloses a preparation method of a nystatin adsorbent based on attapulgite. The preparation method comprises the following specific preparation steps: (1) pretreating attapulgite; (2) coating the surface of the pretreated attapulgite with a layer of dopamine; (3) modifying a layer of bromine initiator on dopamine; (4) preparing a surface imprinting adsorption material with a boron affinity effect by a free radical polymerization method; and (5) carrying out nystatin adsorption test on the material. The adsorption separation material obtained by the preparation method has excellent mass transfer kinetics performance and adsorption efficiency, is relatively low in cost and simple to prepare, has a specific adsorption effect on nystatin, and can be applied to purification of a nystatin crude product. 本发明属于功能材料制备领域,公开了一种基于凹凸棒土的制霉菌素吸附剂的制备方法。具体制备步骤为:(1)将凹凸棒土进行预处理;(2)在预处理后的凹凸棒土表面包裹一层多巴胺;(3)在多巴胺上修饰一层溴引发剂(4)通过自由基聚合的方法制备具有硼亲和作用的表面印迹吸附材料;(5)对材料进