Application of glabridin in preparation of medicine for treating or preventing influenza virus
The invention belongs to the technical field of medicines, and particularly relates to application of glabridin in preparation of a medicine for treating or preventing influenza viruses. The invention provides an application of glabridin in preparation of a medicine for treating or preventing influe...
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Sprache: | chi ; eng |
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Zusammenfassung: | The invention belongs to the technical field of medicines, and particularly relates to application of glabridin in preparation of a medicine for treating or preventing influenza viruses. The invention provides an application of glabridin in preparation of a medicine for treating or preventing influenza virus. The glabridin is combined with a target of influenza virus NP protein through Van der Waals force and hydrogen bonds, has low binding energy of-5.654 kcal/mol and is highly stable in binding, so that replication of influenza viruses can be effectively inhibited, and a good anti-influenza virus effect is achieved. In addition, glabridin is a plant monomer component, is clear in structure, stable in chemical property, easy in quality control and free of obvious toxic and side effects, and can be used as an active component of a natural small-molecule antiviral drug.
本发明属于医药技术领域,特别涉及一种光甘草定在制备治疗或预防流感病毒的药物中的应用。本发明提供了一种光甘草定在制备治疗或预防流感病毒的药物中的应用。光甘草定通过范德华力、氢键与流感病毒NP蛋白的靶标结合,具有-5.654kcal/mol的低结合能,结合高度稳定,从而可以有效的抑制流感 |
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