Liposome with cell marking capability as well as preparation method and application thereof

The invention belongs to the field of nanotechnology, and discloses a liposome with cell marking capability and a preparation method and application thereof, and a cell membrane anchoring unit contained in the liposome is selected from a cholesterol derivative or a long-chain alkane derivative of a lipid-like component; the cell labeling method based on the liposome has the advantages of simplicity, mildness, stability and high efficiency. The invention also provides an application of the lipidosome containing different group derivatized DSPE-PEG. Cells of which active reaction groups are labeled by the lipidosome can mediate the labeling of nanoparticles on the surfaces of the cells; the in-situ activation of the prodrug on the cell surface can be mediated; after the surface of the liposome is modified with a targeting ligand phenylboronic acid, the active targeting of the liposome to a tumor part can be realized, and the liposome has a great application prospect in the fields of cell surface imaging and tum