Application of 4-phenylbutyric acid or derivative thereof in preparation of product for promoting in-vitro embryonic development

The invention discloses application of 4-phenylbutyric acid or a derivative thereof in preparation of a product for promoting in-vitro embryonic development. The component can improve the blastocyst formation rate of an embryo in the embryo development process before implantation, and promote embryo proliferation so as to increase the total cell number of the embryo; the component can also increase the endoplasmic reticulum abundance of early embryos and reduce the endoplasmic reticulum stress level at the same time, so that the function of protecting the endoplasmic reticulum is achieved; in addition, the component can also reduce the level of apoptosis related gene CAS3 in early embryos and inhibit excessive apoptosis of the embryos, so that in-vitro embryo culture quality and developmental ability are improved, and in-vitro embryo culture is facilitated. 本发明公开了4-苯基丁酸或其衍生物在制备促进体外胚胎发育产品中的应用。该成分在植入前胚胎发育的过程中可以提高胚胎的囊胚形成率，并且促进胚胎增殖从而增加胚胎的总细胞数；该成分还可增加早期胚胎的内质网丰度同时降低内质网应激水平，从而起到保护内质网的功能；该成分还可降低早期胚胎中凋亡相关基因CAS3的水平，抑制胚