Synbiotic therapeutic regimens

Provided herein are compositions, methods, strategies, kits, and articles of manufacture useful, inter alia, for treating or preventing diseases, disorders, or conditions that may be associated with inflammation, infection, allergy, immune dysfunction, or dysbiosis of the gut microbiome, such as graft versus host disease (GVHD). In some aspects, the present invention provides a synergistic combination of a prebiotic that is synthetic or derived from human milk and a probiotic strain, such as a strain that can internalize and consume prebiotics, for example, Bifidobacterium longum subsp. Infantis. The present invention provides a synergistic combination of a prebiotic that is synthetic or derived from human milk and a probiotic strain, such as a strain that can internalize and consume prebiotics, for example, Bifidobacterium longum subsp. Infantis. 本文提供了尤其可用于治疗或预防可能与炎症、感染、过敏、免疫功能障碍或肠道微生物组的生态失调相关的疾病、病症或病状，如移植物抗宿主病(GVHD)的组合物、方法、策略、试剂盒和制品。在一些方面，本发明提供了合成或源自人乳的益生元与益生菌菌株，如能够内化和消耗益生元的菌株，例如，长双歧杆菌婴儿亚种(Bifidobacterium l