Improved polyethyleneimine polyethylene glycol carriers

Provided are multimers of a double-stranded RNA and a polymeric conjugate wherein the polymeric conjugate consists of a linear polyethyleneimine covalently linked to one or more polyethylene glycol (PEG) moieties, each PEG moiety being conjugated via a linker to a targeting moiety capable of binding...

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Hauptverfasser: JOUBRAN, SALIM, LEVITZKI, ALEX, ZIEGLER MAYA, TALHAMI ALAA, LANGOUET, YAIR, SHIR, ALEXEI
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creator JOUBRAN, SALIM
LEVITZKI, ALEX
ZIEGLER MAYA
TALHAMI ALAA
LANGOUET, YAIR
SHIR, ALEXEI
description Provided are multimers of a double-stranded RNA and a polymeric conjugate wherein the polymeric conjugate consists of a linear polyethyleneimine covalently linked to one or more polyethylene glycol (PEG) moieties, each PEG moiety being conjugated via a linker to a targeting moiety capable of binding to a cancer antigen. 提供双链RNA和聚合缀合物的多聚物,其中所述聚合缀合物由与一个或多个聚乙二醇(PEG)部分共价连接的线型聚乙烯亚胺组成,各PEG部分经接头与能够结合癌症抗原的靶向部分缀合。
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Improved polyethyleneimine polyethylene glycol carriers
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