Topical roflumilast formulations with antifungal properties

The present invention relates to a method of treating a fungal infection comprising topically administering to a subject in need thereof an antifungal effective amount of roflumilast. Preferably, the topically administered roflumilast is used to treat fungal infections, fungal growth, and/or allergy...

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Bibliographische Detailangaben
Hauptverfasser: KATO SEIICHI, BURKE DENIS R, BURNETT, PAUL, EDWARD, OSBORNE DAVID W
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to a method of treating a fungal infection comprising topically administering to a subject in need thereof an antifungal effective amount of roflumilast. Preferably, the topically administered roflumilast is used to treat fungal infections, fungal growth, and/or allergy to the fungal malassezia. Patients may also suffer from seborrheic dermatitis, dandruff, duopliukumab facial redness, tinea versicolor, pityriasis versicolor, tinea cirrhosa, tinea pedis, tinea unguium, tinea manuum, tinea cruris, tinea corporis, tinea face, tinea capitis and/or tinea difficult to recognize. The topically administered roflumilast is a fast and potent antifungal agent and represents a viable alternative to current antifungal treatments. 本发明涉及治疗真菌感染的方法,其包括向有此需要的受试者局部施用抗真菌有效量的罗氟司特。优选地,局部施用的罗氟司特用于治疗真菌感染、真菌生长和/或对真菌马拉色菌过敏。患者还可能患有脂溢性皮炎、头皮屑、度普利尤单抗面部发红、花斑癣、花斑糠疹、圆癣、足癣、甲癣、手癣、股癣、体癣、面癣、头癣和/或难辨认癣。局部施用的罗氟司特为一种快速且有效的抗真菌剂,并且代表当前抗真菌治疗的一种可行的替代方案。