Method for inducing generation of megakaryocyte and application of megakaryocyte

The invention provides a method for inducing generation of megakaryocytes and application of the megakaryocytes, and belongs to the technical field of cell induced differentiation. According to the method, the placenta tissue is taken as a raw material, nucleated cells containing placenta hematopoietic stem cells are obtained through separation, then the nucleated cells are subjected to amplification and passage, and finally the megakaryocytes are successfully obtained through induction of a specific induction culture medium. According to the method provided by the invention, the problems that the megakaryocyte obtained by in-vitro induced differentiation in the prior art is poor in production performance and cannot meet the platelet demand are solved. The megakaryocyte induced and generated by the method is excellent in production performance, a large number of platelets can be generated, and an effective way is provided for large-scale production of platelet component blood products. 本发明提供了一种诱导生成巨核细胞的方法及其应用