Antiviral nucleoside analogue as well as pharmaceutical composition and application thereof

The invention belongs to the technical field of medicinal chemistry, and particularly relates to an antiviral nucleoside analogue as well as a pharmaceutical composition and application thereof. The structure of the nucleoside analogue is shown in the formula (I), and the nucleoside analogue is good in chemical stability, high in oral bioavailability and remarkable in antiviral activity and can be used for preparing an inhibitor for inhibiting virus replication and/or a medicine for preventing, relieving and/or treating diseases caused by virus infection. # imgabs0 # 本发明属于药物化学技术领域，具体涉及一种抗病毒核苷类似物及其药物组合物和用途。本发明的核苷类似物的结构如式(I)所示，其化学稳定性好，口服生物利用度高，并且具有显著的抗病毒活性，可用于制备抑制病毒复制的抑制剂和/或预防、缓解和/或治疗由病毒感染引起的疾病的药物。#imgabs0#