Methods for treating multiple myeloma

Provided herein are methods of treating multiple myeloma comprising administering a nuclear receptor binding SET domain protein 2 (NSD2) inhibitor to a subject suffering from multiple myeloma. Methods of use are also provided in which it has been previously determined that the multiple myeloma has a...

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Bibliographische Detailangaben
Hauptverfasser: HAGNER, PAUL, R, STONE NICHOLAS, THAKURTA AJAY, FLINT JAMES EDWARD, PIERCIER, WILLIAM, E, ORTIZ-ESTEVES MARILIZ
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided herein are methods of treating multiple myeloma comprising administering a nuclear receptor binding SET domain protein 2 (NSD2) inhibitor to a subject suffering from multiple myeloma. Methods of use are also provided in which it has been previously determined that the multiple myeloma has a 4: 14 chromosomal translocation (t < 4; 14)). 本文提供了治疗多发性骨髓瘤的方法,所述方法包括向患有多发性骨髓瘤的受试者施用核受体结合SET结构域蛋白2(NSD2)抑制剂。还提供了使用方法,其中先前已经确定所述多发性骨髓瘤具有4:14染色体易位(t(4;14))。