Composition for preventing or treating metabolic diseases comprising torasemide and cromoglycin

The present invention relates to a composition for the treatment of metabolic diseases comprising torasemide and tryptophane, according to the present invention, when torasemide and tryptophane are administered in combination compared to the case of treatment with tryptophane alone, it is possible to improve the therapeutic effect of the torasemide and tryptophane. According to the present invention, the weight loss, the insulin resistance reduction, and the liver fat accumulation in a non-alcoholic steatohepatitis (NASH) animal model are significantly reduced, and thus it can be usefully used as a use for preventing or treating metabolic diseases including diabetes, obesity, insulin resistance, and metabolic liver diseases. 本发明涉及一种包含托拉塞米以及色甘酸的用于治疗代谢性疾病的组合物，根据本发明，与单独用色苷酸处理的情况相比，当联合给药托拉塞米和色甘酸时，非酒精性脂肪性肝炎(NASH)动物模型的体重减少、胰岛素抵抗减少以及肝脂肪堆积显著减少，因此具有可以将其有用地用作预防或治疗包括糖尿病、肥胖症、胰岛素抵抗以及代谢性肝病的代谢性疾病的用途的效果。