Detection method of stiripentanol isomer

The invention relates to the technical field of analysis and detection, in particular to a detection method of a stiripentanol isomer. According to the method, high performance liquid chromatography is adopted for detection; chromatographic conditions of the high performance liquid chromatography ar...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SHI JINXIN, DA WEIQIANG, LIU JIE, NIU SHICHONG, YUAN GUANGFENG, YAN YONGNA, DU RUI
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to the technical field of analysis and detection, in particular to a detection method of a stiripentanol isomer. According to the method, high performance liquid chromatography is adopted for detection; chromatographic conditions of the high performance liquid chromatography are as follows: a chromatographic column is an octadecyl silane bonded silica gel chromatographic column; a mobile phase is methanol-0. 18 wt%-0.24 wt% of a sodium pentanesulfonate aqueous solution, and an isocratic elution mode is adopted for elution; the detector is an ultraviolet detector; the detection wavelength is 260 to 270 nm; the flow velocity is 1.0 to 1.3 ml/min. The detection method is high in sensitivity and good in specificity, can detect the stiripentanol and the cis-isomer of the stiripentanol, can be used for quality control of stiripentanol raw materials and preparations of the stiripentanol raw materials, and improves the medication safety of the stiripentanol. 本发明涉分析检测技术领域,尤其涉及一种司替戊醇异构体的检测方法。该方法,采