Cyclopropyl-methyl-containing steroid quaternary ammonium salt compound, intermediate and preparation method and application of cyclopropyl-methyl-containing steroid quaternary ammonium salt compound
The invention discloses a cyclopropyl methyl steroid-containing quaternary ammonium salt compound as shown in a formula (I) and a preparation method thereof, the compound can be applied to preparation of a non-depolarized short-acting muscle relaxation agent, and compared with rocuronium bromide wid...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a cyclopropyl methyl steroid-containing quaternary ammonium salt compound as shown in a formula (I) and a preparation method thereof, the compound can be applied to preparation of a non-depolarized short-acting muscle relaxation agent, and compared with rocuronium bromide widely used clinically at present, the short-acting muscle relaxation agent has the advantages that the onset time is close to the duration time, but the drug metabolism is obviously faster, and the relaxed muscle relaxation agent has a good effect on treating muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle relaxed muscle. The muscle relaxation time is obviously shortened, the better safety is achieved, and the postoperative residual muscle relaxation effect which seriously influences the safety of postoperative patients and has the high occurrence rate can be expect |
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