Synthesis method of 8-oxo-2, 2, 14, 14-tetramethyl pentadecanedioic acid

The invention provides a synthesis method of 8-oxo-2, 2, 14, 14-tetramethyl pentadecanedioic acid, which comprises the following steps: (1) adding water and lithium hydroxide into a reaction container, heating and stirring until the solution is clear; (2) a mixed solution containing 8-oxo-2, 2, 14, 14-tetramethyl pentadecanedioic acid diethyl ester and dimethyl sulfoxide is added into the container, and the mixed solution is added into the container; and (3) stirring the reaction liquid obtained in the previous step, heating to a preset temperature, and stirring for a preset time while keeping the temperature, so as to obtain the 8-oxo-2, 2, 14, 14-tetramethyl pentadecanedioic acid. By utilizing the method, the 8-oxo-2, 2, 14, 14-tetramethyl pentadecanedioic acid can be efficiently synthesized, the product purity is high, impurities are few, the yield is high, organic solvents such as methyl tert-butyl ether do not need to be adopted for refining in the post-treatment process, the method is more environment-f