Adenosine injection and preparation method thereof

The invention relates to an adenosine injection and a preparation method thereof. The adenosine injection is prepared from the following raw materials in percentage by mass: 0.3% of adenosine, 0.8-20% of an osmotic pressure regulator and the balance of water for injection, the preparation method com...

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Hauptverfasser: ZHOU WENWEI, WU MENG, LIAN MENGYUAN, YE YINGJIAN, WANG SHENG, QIAO XIAOFANG, ZHOU HONGJIAN, LI JUNXIA, DANG MING'AN, LIU SONG, ZHAO MINGYANG, LIU ZHENMIN, YUAN CUIYING
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creator ZHOU WENWEI
WU MENG
LIAN MENGYUAN
YE YINGJIAN
WANG SHENG
QIAO XIAOFANG
ZHOU HONGJIAN
LI JUNXIA
DANG MING'AN
LIU SONG
ZHAO MINGYANG
LIU ZHENMIN
YUAN CUIYING
description The invention relates to an adenosine injection and a preparation method thereof. The adenosine injection is prepared from the following raw materials in percentage by mass: 0.3% of adenosine, 0.8-20% of an osmotic pressure regulator and the balance of water for injection, the preparation method comprises the following specific preparation steps: S1, preparing a liquid: adding water for injection which is 70% of the prescription dosage into a liquid preparation container, and adding an osmotic pressure regulator and adenosine which are in the prescription dosage at 60-80 DEG C to obtain an adenosine mixed liquid medicine; step S2: filling; s2, uniformly stirring and mixing the adenosine mixed liquid medicine obtained in the step S1, filtering the liquid medicine through a 0.22 mu m microfiltration membrane, filling the filtered liquid medicine into a colorless medium borosilicate glass ampoule, and carrying out high-temperature flame sealing; and step S3: sterilization. Compared with the prior art, the method
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The adenosine injection is prepared from the following raw materials in percentage by mass: 0.3% of adenosine, 0.8-20% of an osmotic pressure regulator and the balance of water for injection, the preparation method comprises the following specific preparation steps: S1, preparing a liquid: adding water for injection which is 70% of the prescription dosage into a liquid preparation container, and adding an osmotic pressure regulator and adenosine which are in the prescription dosage at 60-80 DEG C to obtain an adenosine mixed liquid medicine; step S2: filling; s2, uniformly stirring and mixing the adenosine mixed liquid medicine obtained in the step S1, filtering the liquid medicine through a 0.22 mu m microfiltration membrane, filling the filtered liquid medicine into a colorless medium borosilicate glass ampoule, and carrying out high-temperature flame sealing; and step S3: sterilization. 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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Adenosine injection and preparation method thereof
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