Adenosine injection and preparation method thereof

The invention relates to an adenosine injection and a preparation method thereof. The adenosine injection is prepared from the following raw materials in percentage by mass: 0.3% of adenosine, 0.8-20% of an osmotic pressure regulator and the balance of water for injection, the preparation method com...

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Hauptverfasser: ZHOU WENWEI, WU MENG, LIAN MENGYUAN, YE YINGJIAN, WANG SHENG, QIAO XIAOFANG, ZHOU HONGJIAN, LI JUNXIA, DANG MING'AN, LIU SONG, ZHAO MINGYANG, LIU ZHENMIN, YUAN CUIYING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to an adenosine injection and a preparation method thereof. The adenosine injection is prepared from the following raw materials in percentage by mass: 0.3% of adenosine, 0.8-20% of an osmotic pressure regulator and the balance of water for injection, the preparation method comprises the following specific preparation steps: S1, preparing a liquid: adding water for injection which is 70% of the prescription dosage into a liquid preparation container, and adding an osmotic pressure regulator and adenosine which are in the prescription dosage at 60-80 DEG C to obtain an adenosine mixed liquid medicine; step S2: filling; s2, uniformly stirring and mixing the adenosine mixed liquid medicine obtained in the step S1, filtering the liquid medicine through a 0.22 mu m microfiltration membrane, filling the filtered liquid medicine into a colorless medium borosilicate glass ampoule, and carrying out high-temperature flame sealing; and step S3: sterilization. Compared with the prior art, the method