Bionic polypeptide based on barnacle biogel protein, self-assembled hydrogel and preparation process and application of self-assembled hydrogel

The invention discloses a biomimetic polypeptide based on barnacle bioglue protein. The amino acid sequence of the biomimetic polypeptide is shown in the specification. The invention also provides the self-assembled hydrogel as well as a preparation process and application thereof. The biomimetic polypeptide based on barnacle biogel protein has excellent gelling ability, and hydrogel with short gelling time, higher storage modulus and higher mechanical strength can be obtained at lower polypeptide concentration. The polypeptide self-assembly environment is simple, and self-assembly can be achieved only through single polypeptide. Moreover, the self-assembled hydrogel disclosed by the invention is good in biocompatibility, can be widely applied to the biomedical fields of drug sustained release, cell culture and the like, and lays a material foundation for developing the biomedical research of the self-assembled hydrogel. 本发明公开了一种基于藤壶生物胶蛋白的仿生多肽，所述仿生多肽的氨基酸序列为。本发明还提供一种自组装水凝胶及其制备工艺、应用。本发明的基于藤壶生物胶蛋白的仿生多肽具有优异的成胶能力，