Aaptamine dimeric alkaloid as well as pharmaceutical composition, preparation method and application thereof
The invention relates to the technical field of marine organisms, and relates to aaptamine dimeric alkaloid as well as a pharmaceutical composition, a preparation method and application thereof. The chemical structural formula of the aaptamine dimeric alkaloid disclosed by the invention is as shown...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | The invention relates to the technical field of marine organisms, and relates to aaptamine dimeric alkaloid as well as a pharmaceutical composition, a preparation method and application thereof. The chemical structural formula of the aaptamine dimeric alkaloid disclosed by the invention is as shown in a general formula I in the specification. The invention provides aaptamine dimeric alkaloid capable of inhibiting the activity of MTH1 protein, and the aaptamine dimeric alkaloid is a novel MTH1 protein inhibitor. # imgabs0 #
本发明涉及海洋生物技术领域，涉及一种aaptamine二聚生物碱及其药物组合物、制备方法和应用。本发明的aaptamine二聚生物碱的化学结构式如通式Ⅰ所示。本发明提出一种具有抑制MTH1蛋白活性的aaptamine二聚生物碱，是一种新型的MTH1蛋白的抑制剂。#imgabs0# |
|---|