Liquid pharmaceutical composition containing teriparatide having excellent stability

The present invention relates to a teriparatide-containing liquid pharmaceutical composition having excellent stability. According to the present invention, as a liquid pharmaceutical preparation of teriparatide or a salt thereof having excellent physical properties, a liquid pharmaceutical preparat...

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Bibliographische Detailangaben
Hauptverfasser: MIYABE KOHEI, MATSUNAWA YASUHIRO, WATANABE NARUMI, YAMAGUCHI TAKAHIRO
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention relates to a teriparatide-containing liquid pharmaceutical composition having excellent stability. According to the present invention, as a liquid pharmaceutical preparation of teriparatide or a salt thereof having excellent physical properties, a liquid pharmaceutical preparation containing teriparatide or a salt thereof and at least one inorganic salt and/or organic salt is provided. The present invention relates to a liquid pharmaceutical preparation containing a component 1 and a component 2, the component 1 being teriparatide or a salt thereof, the component 2 being one or more salts selected from a sodium salt, a calcium salt and a magnesium salt and/or one or more salts selected from a hydrochloride, a hydrobromide, an acetate, a citrate and a carbonate, and the component 2 being a component different from the component 1. 本发明涉及稳定性优异的含有特立帕肽的液态药物组合物。根据本发明,作为在物性的方面优异的特立帕肽或其盐的液态药物制剂,提供了含有特立帕肽或其盐以及至少一种以上的无机盐和/或有机盐的液态药物制剂。一种液态药物制剂,其中,该药物制剂含有成分1和成分2,成分1)特立帕肽或其盐,成分2)选自钠盐、钙盐以及镁盐中的1种以上的盐和/