Crystal form of macloxvir intermediate compound and preparation method thereof

The invention relates to a crystal form I for short of a hydrate of p-toluenesulfonate (formula 1) of a key intermediate compound of a novel anti-influenza prodrug macavir, a preparation method of the crystal form I, a crystal form II for short of p-toluenesulfonate of the intermediate compound (formula 2), and a preparation method of the crystal form II. The crystals of the crystal form I and the crystal form II are determined to be in two crystal forms through powder X-ray diffraction detection. The two crystal forms provided by the invention have the advantages that p-toluenesulfonate of an intermediate compound of the macarovir can be separated and purified from a reaction solution, and the two crystal forms are high in purity, good in stability and simple in preparation process, have very positive significance for improving the quality of the macarovir, and are very suitable for industrial production. 本发明涉及一种新型抗流感前体药物玛巴洛沙韦的关键中间体化合物对甲苯磺酸盐的水合物（式1）的晶型，简称晶型Ⅰ，及其制备方法和该中间体化合物的对甲苯磺酸盐（式2）的晶型，简称晶型Ⅱ，及其制备方法。本发明的晶型Ⅰ和