Polyphenol-loaded bionic mussel photo-thermal hydrogel dressing as well as preparation method and application thereof

The invention belongs to the technical field of diabetes wound healing, and discloses a polyphenol-loaded bionic mussel photo-thermal hydrogel dressing as well as a preparation method and application thereof, and the hydrogel can simultaneously meet treatment requirements of three major pathological bases of a diabetes wound. The hydrogel is based on gelatin, active polyphenol is modified and loaded through the dopamine polymerization effect of bionic mussels, and targeted treatment of three major pathological bases of diabetic wounds can be achieved. The preparation method is simple, is convenient for large-scale preparation and is applied to household and clinical treatment of diabetic wounds. 本发明属于糖尿病创面愈合技术领域，公开了一种负载多酚的的仿生贻贝光热水凝胶敷料及其制备方法与应用，该水凝胶能同时满足糖尿病创面三大病理基础的治疗需求。该水凝胶以明胶为基础，通过仿生贻贝的多巴胺聚合作用修饰并负载活性多酚，可实现对糖尿病创面三大病理基础的针对性治疗。本制备方法简单，便于大规模制备并应用于糖尿病创面的居家与临床治疗。