Application of exosome protein in preparation of product for auxiliary diagnosis of interstitial lung disease

The invention discloses application of exosome protein in preparation of a product for auxiliary diagnosis of interstitial lung diseases, and belongs to the technical field of protein detection, the exosome protein is selected from LAMC1, PSMA3 and PTPRG on exosome, and the product comprises a sampl...

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Hauptverfasser: YAO LINKANG, WU TURONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of exosome protein in preparation of a product for auxiliary diagnosis of interstitial lung diseases, and belongs to the technical field of protein detection, the exosome protein is selected from LAMC1, PSMA3 and PTPRG on exosome, and the product comprises a sample treating fluid, a magnetic bead coating substance, a detection antibody marked by a luminous substance, a luminous substrate and a protein calibrator. The invention provides application of LAMC1, PSMA3 and PTPRG on exosomes in preparation of products for auxiliary diagnosis of interstitial lung diseases, and the LAMC1, PSMA3 and PTPRG have higher specificity and sensitivity and have important clinical value and popularization prospect in early diagnosis of interstitial lung diseases. 本发明公开了外泌体蛋白在制备辅助诊断间质性肺疾病产品中的应用,属于蛋白质检测技术领域,所述外泌体蛋白选自外泌体上LAMC1、PSMA3、PTPRG,所述产品包括样本处理液、磁珠包被物、发光物标记的检测抗体、发光底物、蛋白校准品。本发明提供了外泌体上LAMC1、PSMA3、PTPRG在制备辅助诊断间质性肺疾病产品的应用,有更高的特异性和灵敏度,在间质性肺疾病早期诊断中具有重要的临床价值和推广前景。