Biomarker for atopic dermatitis and application thereof

The invention discloses a biomarker for atopic dermatitis and application of the biomarker. The inventor of the invention adopts liquid chromatography-mass spectrometry and data independent acquisition technology detection to find that the expression of aminolevulinic acid dehydratase (ALAD) in the blood of an atopic dermatitis patient is obviously reduced, and the ALAD can be well used as a marker for atopic dermatitis diagnosis and reaction severity, can provide objective laboratory indexes for disease diagnosis, and has a good application prospect. Precise treatment can be realized, and the method has important significance for improving the clinical curative effect. 本发明公开了特应性皮炎的生物标志物及其应用。本发明的发明人采用液质联用、数据非依赖性采集技术检测，发现特应性皮炎患者血液中氨基乙酰丙酸脱水酶(ALAD)表达明显下降，其能够很好作为特应性皮炎诊断和反应严重程度的标志物，可以为疾病的诊断提供客观的实验室指标，有助于实现精准治疗，对于提高临床疗效有重要意义。