Tilmicosin injection and preparation method thereof
The invention provides a tilmicosin injection. The tilmicosin injection comprises tilmicosin and a pharmaceutically acceptable organic solvent, wherein the pharmaceutically acceptable organic solvent is selected from one or more of alpha-pyrrolidone, ethanol, propylene glycol, dimethylformamide and...
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creator | PENG GUOPING ZHANG LIANG YAN JIAO ZOU, YONGZHONG PI YANHUA MAO YINHUA MIAO CHAO ZHU DECHANG |
description | The invention provides a tilmicosin injection. The tilmicosin injection comprises tilmicosin and a pharmaceutically acceptable organic solvent, wherein the pharmaceutically acceptable organic solvent is selected from one or more of alpha-pyrrolidone, ethanol, propylene glycol, dimethylformamide and benzyl alcohol. In addition, the invention also provides a preparation method. According to the tilmicosin injection, tilmicosin with the content larger than 98% can be adopted as a raw material for production, compared with tilmicosin phosphate (with the content smaller than 77%), the use amount of the raw material in liquid medicine is greatly reduced, and the viscosity of the liquid medicine is greatly reduced to a certain degree.
本发明提供一种替米考星注射液,包括替米考星、药物上可接受的有机溶媒;其中所述药物上可接受的有机溶媒选自α-吡咯烷酮、乙醇、丙二醇、二甲基甲酰胺、苯甲醇的一种或几种。另外,还提供其制备方法。本发明替米考星注射液,可以采用含量大于98%替米考星作为原料进行生产,相比使用磷酸替米考星(含量低于77%)大大减少了药液中原料的使用量,在一定程度上大大减少药液的黏稠度。 |
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本发明提供一种替米考星注射液,包括替米考星、药物上可接受的有机溶媒;其中所述药物上可接受的有机溶媒选自α-吡咯烷酮、乙醇、丙二醇、二甲基甲酰胺、苯甲醇的一种或几种。另外,还提供其制备方法。本发明替米考星注射液,可以采用含量大于98%替米考星作为原料进行生产,相比使用磷酸替米考星(含量低于77%)大大减少了药液中原料的使用量,在一定程度上大大减少药液的黏稠度。</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231013&DB=EPODOC&CC=CN&NR=116869929A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231013&DB=EPODOC&CC=CN&NR=116869929A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PENG GUOPING</creatorcontrib><creatorcontrib>ZHANG LIANG</creatorcontrib><creatorcontrib>YAN JIAO</creatorcontrib><creatorcontrib>ZOU, YONGZHONG</creatorcontrib><creatorcontrib>PI YANHUA</creatorcontrib><creatorcontrib>MAO YINHUA</creatorcontrib><creatorcontrib>MIAO CHAO</creatorcontrib><creatorcontrib>ZHU DECHANG</creatorcontrib><title>Tilmicosin injection and preparation method thereof</title><description>The invention provides a tilmicosin injection. The tilmicosin injection comprises tilmicosin and a pharmaceutically acceptable organic solvent, wherein the pharmaceutically acceptable organic solvent is selected from one or more of alpha-pyrrolidone, ethanol, propylene glycol, dimethylformamide and benzyl alcohol. In addition, the invention also provides a preparation method. According to the tilmicosin injection, tilmicosin with the content larger than 98% can be adopted as a raw material for production, compared with tilmicosin phosphate (with the content smaller than 77%), the use amount of the raw material in liquid medicine is greatly reduced, and the viscosity of the liquid medicine is greatly reduced to a certain degree.
本发明提供一种替米考星注射液,包括替米考星、药物上可接受的有机溶媒;其中所述药物上可接受的有机溶媒选自α-吡咯烷酮、乙醇、丙二醇、二甲基甲酰胺、苯甲醇的一种或几种。另外,还提供其制备方法。本发明替米考星注射液,可以采用含量大于98%替米考星作为原料进行生产,相比使用磷酸替米考星(含量低于77%)大大减少了药液中原料的使用量,在一定程度上大大减少药液的黏稠度。</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAOyczJzUzOL87MU8jMy0pNLsnMz1NIzEtRKChKLUgsSgTzc1NLMvJTFEoyUotS89N4GFjTEnOKU3mhNDeDoptriLOHbmpBfnxqcUFicmpeakm8s5-hoZmFmaWlkaWjMTFqADXMLQQ</recordid><startdate>20231013</startdate><enddate>20231013</enddate><creator>PENG GUOPING</creator><creator>ZHANG LIANG</creator><creator>YAN JIAO</creator><creator>ZOU, YONGZHONG</creator><creator>PI YANHUA</creator><creator>MAO YINHUA</creator><creator>MIAO CHAO</creator><creator>ZHU DECHANG</creator><scope>EVB</scope></search><sort><creationdate>20231013</creationdate><title>Tilmicosin injection and preparation method thereof</title><author>PENG GUOPING ; ZHANG LIANG ; YAN JIAO ; ZOU, YONGZHONG ; PI YANHUA ; MAO YINHUA ; MIAO CHAO ; ZHU DECHANG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN116869929A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>PENG GUOPING</creatorcontrib><creatorcontrib>ZHANG LIANG</creatorcontrib><creatorcontrib>YAN JIAO</creatorcontrib><creatorcontrib>ZOU, YONGZHONG</creatorcontrib><creatorcontrib>PI YANHUA</creatorcontrib><creatorcontrib>MAO YINHUA</creatorcontrib><creatorcontrib>MIAO CHAO</creatorcontrib><creatorcontrib>ZHU DECHANG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PENG GUOPING</au><au>ZHANG LIANG</au><au>YAN JIAO</au><au>ZOU, YONGZHONG</au><au>PI YANHUA</au><au>MAO YINHUA</au><au>MIAO CHAO</au><au>ZHU DECHANG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Tilmicosin injection and preparation method thereof</title><date>2023-10-13</date><risdate>2023</risdate><abstract>The invention provides a tilmicosin injection. The tilmicosin injection comprises tilmicosin and a pharmaceutically acceptable organic solvent, wherein the pharmaceutically acceptable organic solvent is selected from one or more of alpha-pyrrolidone, ethanol, propylene glycol, dimethylformamide and benzyl alcohol. In addition, the invention also provides a preparation method. According to the tilmicosin injection, tilmicosin with the content larger than 98% can be adopted as a raw material for production, compared with tilmicosin phosphate (with the content smaller than 77%), the use amount of the raw material in liquid medicine is greatly reduced, and the viscosity of the liquid medicine is greatly reduced to a certain degree.
本发明提供一种替米考星注射液,包括替米考星、药物上可接受的有机溶媒;其中所述药物上可接受的有机溶媒选自α-吡咯烷酮、乙醇、丙二醇、二甲基甲酰胺、苯甲醇的一种或几种。另外,还提供其制备方法。本发明替米考星注射液,可以采用含量大于98%替米考星作为原料进行生产,相比使用磷酸替米考星(含量低于77%)大大减少了药液中原料的使用量,在一定程度上大大减少药液的黏稠度。</abstract><oa>free_for_read</oa></addata></record> |
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title | Tilmicosin injection and preparation method thereof |
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