Method for constructing animal model of intestinal stress injury caused by oxygen deficit

The invention provides a method for constructing an animal model of intestinal stress injury caused by oxygen deficit. The method comprises the following steps: feeding an animal in an oxygen deficit environment; wherein the oxygen concentration in the anoxic environment is 5-15% by volume. According to the method disclosed by the invention, the hypoxia intestinal stress injury animal model is successfully established, the verification and evaluation of the model are effectively completed, and an experimental foundation can be laid for further research on pathogenesis of related intestinal diseases caused in a low-oxygen environment. In addition, the method is easy to operate, short in modeling period, low in cost and suitable for application and popularization. 本发明提出了构建缺氧导致肠道应激损伤的动物模型的方法，所述方法包括：将动物置于缺氧环境中饲养；其中，所述缺氧环境中的氧气浓度为5~15体积%。利用本发明的方法成功建立了一种缺氧肠道应激损伤动物模型并有效完成模型的验证和评价，可为低氧环境下引发肠道相关疾病致病机理的进一步研究奠定实验基础。并且，本发明的方法操作简单、建模周期短、成本低，适于推广应用。