COMPOSITIONS, METHODS, SYSTEMS AND/OR KITS FOR DETECTING ANTIMICROBIAL RESISTANCE IN BACTERIA

Provided herein are compositions, methods, systems and/or kits for detecting bacteria expressing enzymes that confer resistance to antimicrobial agents. Certain embodiments of the compositions, methods, systems, and/or kits of the present disclosure relate to the detection of carbapenemase producing...

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Bibliographische Detailangaben
Hauptverfasser: TURNER DAVID J, KIRCHER SUSAN M, ALRASHIDI-BROOKS FATIMA, BRASSO, WILLIAM, B
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided herein are compositions, methods, systems and/or kits for detecting bacteria expressing enzymes that confer resistance to antimicrobial agents. Certain embodiments of the compositions, methods, systems, and/or kits of the present disclosure relate to the detection of carbapenemase producing gram negative bacteria. Certain embodiments of the compositions, methods, systems, and/or kits of the present disclosure relate to the detection of Ambler class A, class B, and/or class D carbapenemase producing intestinal bacteria and non-fermentative gram-negative rod bacteria. 本文提供了用于检测表达赋予对抗微生物剂抗性的酶的细菌的组合物、方法、系统和/或试剂盒。本公开的组合物、方法、系统和/或试剂盒的某些实施方案涉及产碳青霉烯酶的革兰氏阴性细菌的检测。本公开的组合物、方法、系统和/或试剂盒的某些实施方案涉及产Ambler A类、B类和/或D类碳青霉烯酶的肠道细菌和非发酵性革兰氏阴性杆状菌的检测。