Genetically engineered cell and preparation method thereof

Genetically engineered cell and preparation method thereof

Provided are CRISPR/CAS related methods, compositions, and components for editing or modulating the expression of a target nucleic acid sequence, and uses thereof in combination with cancer immunotherapy including adoptive metastasis of engineered T cells or T cell precursors. 提供了用于编辑靶核酸序列或调节靶核酸序列表达...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SATHER BLYTHE, RUBIO, EUGENIO, M, FRIEDLAND ARI E, NYE CHRIS, BUMCROT DAVID A, MADER, MARY, L, JONES JUSTIN, SALMON RUTH, WESTED, GLEN, G
Format: Patent
Sprache:chi ; eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Provided are CRISPR/CAS related methods, compositions, and components for editing or modulating the expression of a target nucleic acid sequence, and uses thereof in combination with cancer immunotherapy including adoptive metastasis of engineered T cells or T cell precursors. 提供了用于编辑靶核酸序列或调节靶核酸序列表达的CRISPR/CAS相关方法、组合物和组分，及其与包括工程化T细胞或T细胞前体的过继转移的癌症免疫疗法结合的应用。